FREE SHIPPING AVAILABLE ON ALL DOMESTIC ORDERS

Search Login

SEARCH

EXO PLUS® Anti-Aging Cream

The Most Advanced Age-Defying Treatment

EXO PLUS™ is a potent anti-aging cream designed to reverse visible signs of aging and dramatically improve skin tone and elasticity. This is a powerful tool to combat photo-aging and promote regeneration. Formulated with the highest concentration of our patented eXo³ Exosomes, this advanced treatment targets both the intrinsic and extrinsic drivers of aging—from oxidative stress and inflammation to hormonal changes and environmental exposure.

eXo³ Exosomes: Your Skin's Cellular Superpower

Not all exosomes are created equal. eXo³ Exosomes are engineered from bioidentical stem cell sources and optimized through patented manufacturing methods to enhance their regenerative performance. They carry essential proteins, growth factors, and nucleic acids that fuse with your skin cells to:

  • Stimulate collagen synthesis and fibroblast proliferation
  • Reduce the appearance of fine lines and wrinkles
  • Improve elasticity and firmness
  • Brighten and even skin tone while smoothing texture and improving thickness
  • Defend against and repair environmental damage and oxidative stress
  • Deeply hydrate while strengthening and rebuilding the skin barrier
  • Promote healthy cell turnover and optimal skin regeneration

Size: 50ML / 1.7 fl oz.
KEY INGREDIENTS

eXo³ Exosomes
At the heart of EXO PLUS™ is its proprietary eXo³ Exosome Technology. These bioactive nanoparticles are derived from stem cells and engineered to deliver targeted repair and rejuvenation. They:

  • Stimulate collagen production and fibroblast proliferation to reduce fine lines and wrinkles

  • Modulate inflammatory responses to calm redness and irritation

  • Deliver essential lipids, growth factors, nucleic acids, and proteins to nourish and reinforce skin barrier function

Hyaluronic Acid
Multi-molecular weights deliver instant and long-term hydration, plump fine lines, and boost natural hyaluronic acid production.

Collagen-Building Peptides & Proteins
Support dermal matrix strength and elasticity while improving skin tone and texture.

Retinyl Palmitate (Provitamin A)
A gentler, stabilized retinol derivative that:

  • Promotes skin cell turnover and smoothness

  • Diminishes wrinkles and improves texture

  • Helps fade hyperpigmentation and blemishes

  • Provides antioxidant protection

Essential Fatty Acids
A skin-restoring complex of Omegas 3, 6, 7, and 9 that:

  • Rebuild ceramides and support the lipid barrier

  • Improve elasticity and suppleness

  • Provide anti-inflammatory and antibacterial benefits

ESS Vitamin Complex (A, C, D3, E)
A powerhouse of antioxidants and skin-renewing vitamins that:

  • Boost collagen synthesis

  • Brighten skin tone and reduce dark spots

  • Protect against oxidative stress

  • Strengthen the skin’s immune defense

Coconut Oil
Deeply hydrates and soothes with natural antimicrobial and anti-inflammatory properties.

Grape Seed Oil
Rich in linoleic acid and antioxidants to improve elasticity, reduce inflammation, and support a clear complexion.

Brown Algae Extract (BAE)
Delivers potent antioxidant and UV-protective benefits while enhancing hydration and oxygenation for youthful glow.

Botanical Super Extracts
Including Noni Fruit and Agastache Mexicana, these plant actives soothe irritation, calm inflammation, and promote microbiome balance.

CCT & OM Fatty Acids
Nourish and fortify the skin’s protective barrier without clogging pores—ideal for all skin types.

TEXTURE
  • Rich, yet smooth and weightless, this cream melts seamlessly into the skin, leaving it soft, hydrated, and perfectly prepped. The silky texture wears beautifully alone or as a base under skincare and makeup.
INGREDIENTS LIST

Water, Cocos Nucifera (Coconut) Oil, Caprylic/Capric Triglyceride (Fatty Acid), Octyldodecyl Myristate (Fatty Acid), Dimethicone, Glycerin, PEG-8 Beeswax, Human Adipose Stromal Cell Exosomes (exo3 Exosomes), Vitis Vinifera (Grape) Seed Oil, Macadamia Ternifolia Seed Oil, Eucalyptus Globulus Leaf Oil, Acrylates/Acrylamide Copolymer, Mineral Oil, Polysorbate 85, Cetyl Alcohol, Ceteth-20, Steareth-20, Phenoxyethanol, Propanediol, Glyceryl Monostearate, Allantoin, Citric Acid, Morinda Citrifolia (Noni) Fruit Juice, Agastache Mexicana Flower/Leaf/Stem Extract, Algae Extract (Sea Kelp), Chondrus Crispus Extract (Irish Sea Moss), Ulva Lactuca Extract (Sea Lettuce) , Undaria Pinnatifida Extract (Japanese Wakame), Laminaria Digitata Extract (Brown Algae), Sodium Hyaluronate, Ascorbic Acid (Vitamin C), Retinyl Palmitate (Vitamin A), Tocopheryl Acetate (Vitamin E), Cholecalciferol (Vitamin D3)

eXo³ Exosomes are a true anti-aging powerhouse—engineered to support skin health, rejuvenation, and the visible reduction of aging signs.

Sourced from bioidentical stem cell origins, these exosomes are enhanced through Exoceuticals’ proprietary manufacturing methods to deliver superior regenerative benefits. This isn’t copycat science—our patented process modulates the exosomal cargo for optimal skin performance. Pre-clinical and clinical studies show that eXo³ Exosomes restore the skin’s natural regenerative functions by:

• Promotes collagen synthesis to support skin firmness
• Improves skin elasticity for a more lifted appearance
• Reduces the appearance of fine lines and wrinkles
• Helps calm age-related inflammation and oxidative stress

READ MORE ABOUT OUR SCIENCE

HOW TO USE

  1. Cleanse your face thoroughly before application.
  2. Dispense a pearl-sized amount of cream onto your fingertips.
  3. Gently massage into the face and neck using upward motions twice daily (morning and evening).
  4. For superior results, we recommend pairing it with our EXO H-SERUM™ and applying after the serum.

NEXT GEN NATURALS™

SEA KELP

A jewel from the ocean's depths, it is celebrated for its unparalleled ability to hydrate, soothe, and detoxify the skin.It fortifies the skin's barrier, promoting a firm, smooth texture.

NONI FRUIT

A tropical wonder packed with over 200 phytonutrients, vitamins, and minerals.Its powerful anti-inflammatory properties help to renew skin cells, leaving the skin glowing with vitality.

SEA LETTUCE

This vibrant green algae aids in soothing inflammation, promoting collagen synthesis, and enhancing skin's natural luminosity for a refreshed, youthful appearance.

BROWN ALGAE

Rich in antioxidants, vitamins, and minerals that revitalize the skin. Its remarkable hydrating properties make it an essential ingredient for a luminous, youthful complexion.

IRISH SEA MOSS

Its natural ability to hydrate and support the skin's elasticity makes it a key ingredient for achieving a smooth, radiant complexion that defies the signs of aging.

AGASTACHE MEXICANA PLANT

Agastache Mexicana Plant, revered for its soothing properties. It is a botanical gem that offers a calming oasis for stressed and sensitive skin. It helps to reduce redness and protect the skin promoting a complexion that is both serene and radiant.

A REVOLUTIONARY TECHNOLOGY: UNLOCKING THE SKIN’S POTENTIAL WITH SCIENTIFIC PRECISION

“What sets Exoceuticals® apart is its scientifically driven formula. Instead of chasing trends, we utilize a unique and proprietary technology that combines eXo3 exosomes with botanicals and next generation naturals activating the skin's innate rejuvenation processes.”

—DR. ROBIN SMITH

FREQUENTLY ASKED QUESTIONS

EXO PLUS®️ Anti-aging Cream is Extra.
  • Extra Repair
  • Extra Restoration

    Extra Rejuvenation

  • Powered by extra inclusion; the highest concentration of eXo3 Exosomes, bioactive nanoparticles involved in multiple biologic and cellular activities of the skin, to provide the regenerative natural resources for damaged or aging skin with machine-like efficiency.

    Exoceuticals® ESS Vitamin Blend™ is a proprietary blend of key essential vitamins- Vitamins A, C, D and E: an “alphabet soup” of nutrients that promote skin health from the inside-out. Not all vitamins affect skin health, but certain vitamins are essential to the skin, as they provide the necessary building blocks needed for natural skin cell functions and to help the skin repair itself when damaged. Vitamins A, C, D, and E especially can play a role in skin health.

    Human skin has an extraordinary superpower: the ability to repair and regenerate itself.Skin regeneration is an innate physical process that occurs on a cellular level, with skin cells constantly healing and replacing themselves.Whether through aging, environmental damage, simple wear and tear, injury or disease, the skin’s integrity and function can be compromised and its capacity to regenerate diminishes.

    Understanding the cellular science behind your skin’s life cycle and regenerative processes, Exoceuticals® is focused on the novel signaling aspects of exosomes involved in multiple biologic and cellular activities of the skin.

    Designed to provide the optimal natural resources for your skin to target structural integrity and cellular dysfunction, Exoceuticals® delivers patented exosome technology engineered to restore and enhance the power of the body's innate mechanisms of repair and regeneration.

    Water, Cocos Nucifera (Coconut) Oil, Caprylic/Capric Triglyceride (Fatty Acid), Octyldodecyl Myristate (Fatty Acid), Dimethicone, Glycerin, PEG-8 Beeswax, Human Adipose Stromal Cell Exosomes (exo3 Exosomes), Vitis Vinifera (Grape) Seed Oil, Macadamia Ternifolia Seed Oil, Eucalyptus Globulus Leaf Oil, Acrylates/Acrylamide Copolymer, Mineral Oil, Polysorbate 85, Cetyl Alcohol, Ceteth-20, Steareth-20, Phenoxyethanol, Propanediol, Glyceryl Monostearate, Allantoin, Citric Acid, Morinda Citrifolia (Noni) Fruit Juice, Agastache Mexicana Flower/Leaf/Stem Extract, Algae Extract (Sea Kelp), Chondrus Crispus Extract (Irish Sea Moss), Ulva Lactuca Extract (Sea Lettuce) , Undaria Pinnatifida Extract (Japanese Wakame), Laminaria Digitata Extract (Brown Algae), Sodium Hyaluronate, Ascorbic Acid (Vitamin C), Retinyl Palmitate (Vitamin A), Tocopheryl Acetate (Vitamin E), Cholecalciferol (Vitamin D3).